Imidazole-buffered cardioplegic solution

Cardioplegic solution challenges.

Oxygenation of a Crystalloid Cardioplegic Solution

_____________ _ The purpose of this study is to compare the effectiveness of an alternative method of oxygenating a crystalloid cardioplegic solution to the use of a bubble oxygenator. Five hundred milliliters of 100% oxygen was introduced, using sterile technique, into 100 ml bags of Ringer's solution at varying temperatures (20°, 10°, and 4°C). The contents of the bags were shaken for one min...

Polarizing cardioplegic solution: state of the art

The meaning of the term “cardioplegia” is “lesion, attack, wound or blow”, very different to how it is most commonly understood in most heart centers, where it relates to cardiac protection. Thus, “cardioplegic solution” is better defined as a solution capable of inducing controlled cardiac arrest. Cardiac arrest induced by cardioplegic solutions can occur by hyperpolarization, depolarization o...

Development of cardioplegic solution without potassium: experimental study in rat

INTRODUCTION Myocardial preservation during open heart surgeries and harvesting for transplant are of great importance. The heart at the end of procedure has to resume its functions as soon as possible. All cardioplegic solutions are based on potassium for induction of cardioplegic arrest. OBJECTIVE To assess a cardioplegic solution with no potassium addition to the formula with two other com...

Solution-phase synthesis of pyrrole-imidazole polyamides.

Pyrrole-imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on a micromole scale sufficient for biophysical characterizations and cell culture studies. In order to produce gram-scale quantities necessary f...